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Leadgene Leadgene
Anti-SARS-CoV & CoV-2 Spike IgM Antibody [Clone CR3022]
Catalog Number

LDG0081YA

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  • Overview

    Description

    Human anti-SARS-CoV-2 Spike Antibody [CR3022] recognizes human SARS-CoV and CoV-2 spike protein with high affinity. The binding site is amino acids 318-510 (RBD, Receptor Binding Domain) in the S1 subunit of the spike protein. Coronavirus spike protein conducts the process that interacts with cellular receptor and membrane fusion to allow virus entering into target cells. Spike protein also can be used to define the specificity of the virus and be used as a critical target for vaccine design. The glycosylated spike protein can be detected in the virus-infected cell and cell culture medium. The RBD is responsible for recognizing the cell surface receptor.

    Product Note

    Recommended dilution factor:
    ELISA: 1:5000-20000
    NTRL: Assay dependent
    SPR: Assay dependent
    Crystallography: Assay dependent

    Note: Working dilution for specific application should be determined by the investigator to obtain the best conditions.

  • Specifications
    • Clonality

      Recombinant Human IgM

      Isotype

      IgM

    • Clone Name

      clone CR3022

      Reactivity

      SARS-CoV & CoV-2

    • Application

      ELISA, NTRL, SPR, Crystallography

      Conjugation

      Unconjugated

    • Concentration

      0.5 mg/mL

      Storage Buffer

      Phosphate Buffered Saline, pH 7.4.

    • Specificity

      Spike protein

      Form

      Liquid

  • Instruction
    • Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at 2-8°C for long term storage.

      Stability & Storage

      This product is stable after storage at:

      • 2-8°C for 6 months under sterile conditions from date of receipt.

      Briefly centrifuge vials before opening.

  • Image
    ELISA titration of Human anti-SARS-CoV & CoV-2 Spike Antibody (IgM)

    ELISA titration of Human anti-SARS-CoV & CoV-2 Spike Antibody (IgM)

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  • Datasheet & Documents
    MSDS
    Manual
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