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Species of Origin
Human
Expression System
HEK293
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Affinity Tag
Mouse IgG2b Fc Tag (C-term)
Storage Buffer
Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
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Purity
>98% as determined by SDS-PAGE analysis.
Molecular weight
The protein has a calculated MW of 109.67 kDa.
The protein migrates as 120-170 kDa under reducing condition (SDS-PAGE analysis). -
Endotoxin Level
<0.1 EU per 1 μg of the protein by the LAL method.
Form
Lyophilized
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Specifications
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Background
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Background
Angiotensin-Converting Enzyme 2 (ACE2) has a function as an enzyme that hydrolysis the angiotensin II into angiotensin which do the effect of anti-oxidation and anti-inflammatory in cardiovascular system through the inhibition of MAPK pathway and TGF β signaling pathway. ACE2 is highly expression in intestines, kidney, and heart. It is also fonud highy expression in patients with lung cancer.
Synonyms
Angiotensin-converting enzyme 2, Angiotensin-converting enzyme homolog, ACEH, Angiotensin-converting enzyme-related carboxypeptidase, ACE-related carboxypeptidase, Metalloprotease MPROT15
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Uniprot ID
#Q9BYF1
Sequence Note
Gln18-Ser740
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Instruction
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Reconstitution
It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.
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Stability & Storage
This product is stable after storage at:
- -20°C for 12 months in lyophilized state from date of receipt.
- -20°C or -80°C for 1 month under sterile conditions after reconstitution.
Avoid repeated freeze/thaw cycles.
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Review
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Publication
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Datasheet & Documents
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Disclaimer:For Research Use or Further Manufacturing Only.