Human FIXa, His Tag, CHO

Catalog Number

LDG029PHM

Datasheet

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• Specifications

  • Species of Origin

    Human

    Expression System

    CHO

  • Affinity Tag

    His Tag (C-term)

    Storage Buffer

    Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

  • Purity

    >90% as determined by SDS-PAGE analysis.

    Molecular weight

    The protein has a calculated MW of 49.54 kDa.
    The protein migrates as 50-60 kDa under reducing condition (SDS-PAGE analysis).

  • Endotoxin Level

    <0.1 EU per 1 μg of the protein by the LAL method.

    Mycoplasma

    Not detected

  • Form

    Lyophilized

• Background

  • Background

    FIXa (Factor IXa) protein is a serine protease involved in the coagulation cascade. Upon activation by Factor XIa or tissue factor-Factor VIIa complex, FIXa forms a complex with Factor VIIIa on phospholipid surfaces. This complex activates Factor X to Xa, ultimately leading to the formation of thrombin and fibrin clot formation. FIXa deficiency results in hemophilia B. Targeting FIXa activity is a therapeutic approach for controlling blood coagulation in hemophilia treatment. Understanding FIXa's role in hemostasis is crucial for developing hemophilia therapies and managing thrombotic disorders.

    Synonyms

    Coagulation factor IX, Christmas factor, Plasma thromboplastin component (PTC)

  • Uniprot ID

    P00740

    Sequence Note

    Met1-Thr461

• Instruction

  • Reconstitution

    It is recommended to reconstitute the lyophilized protein in 4 mM HCl to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

    Shipping

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

  • Stability & Storage

    This product is stable after storage at:

    • -20°C for 12 months in lyophilized state from date of receipt.
    • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

    Avoid repeated freeze/thaw cycles.

• Image

  SDS-PAGE analysis of recombinant human FIXa.

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• Datasheet & Documents

  Datasheet

  MSDS

  Manual

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Disclaimer：For Research Use or Further Manufacturing Only.