Human FX, His Tag, CHO

Catalog Number

LDG030PHM

Datasheet

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• Specifications

  • Species of Origin

    Human

    Expression System

    CHO

  • Affinity Tag

    His Tag (N-term)

    Storage Buffer

    Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

  • Purity

    >90% as determined by SDS-PAGE analysis.

    Molecular weight

    The protein has a calculated MW of 16.97 kDa.
    The protein migrates as 15-20 kDa under reducing condition (SDS-PAGE analysis).

  • Endotoxin Level

    <0.1 EU per 1 μg of the protein by the LAL method.

    Mycoplasma

    Not detected

  • Form

    Lyophilized

• Background

  • Background

    Factor X (FX), also known as Stuart factor, is a vitamin K-dependent serine protease essential for blood coagulation. Upon activation, FX is converted into its active form, Factor Xa (FXa), which plays a pivotal role in the coagulation cascade by catalyzing the conversion of prothrombin to thrombin. Thrombin, in turn, converts fibrinogen into fibrin, leading to the formation of a stable blood clot. Dysregulation of FX activity can result in bleeding disorders or thrombotic events. Understanding FX's role in hemostasis is crucial for developing therapies for coagulation disorders and managing thrombotic conditions.

    Synonyms

    Coagulation factor X, Stuart factor, Stuart-Prower factor

  • Uniprot ID

    P00742

    Sequence Note

    Ala41-Arg182

• Instruction

  • Reconstitution

    It is recommended to reconstitute the lyophilized protein in 4 mM HCl to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

    Shipping

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

  • Stability & Storage

    This product is stable after storage at:

    • -20°C for 12 months in lyophilized state from date of receipt.
    • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

    Avoid repeated freeze/thaw cycles.

• Image

  SDS-PAGE analysis of recombinant human FX.

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• Datasheet & Documents

  Datasheet

  MSDS

  Manual

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Disclaimer：For Research Use or Further Manufacturing Only.