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Leadgene Leadgene
Human Galectin-16, His Tag, E. coli
Catalog Number

LDG151PHE

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  • Specifications
    • Species of Origin

      Human

      Expression System

      Escherichia coli

    • Affinity Tag

      His Tag (N-term)

      Storage Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >98% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 17.4 kDa.
      The protein migrates as 18 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin Level

      <0.1 EU per 1 μg of the protein by the LAL method.

      Form

      Lyophilized

  • Background
    • Background

      Galectin-16 (Gal-16) is a lectin family member and is one of the prototype galectins, but it exists as a monomer, and it is remarkably different from other prototype galectins in β-galactoside binding. Like galectin-13 and galectin-14, Galectin-16 is expressed in the placenta, contributing to T cell apoptosis, immune regulation, and immune tolerance, which is indispensable for fetal development. The molecular mechanism has been demonstrated that galectin-16 forms complex with c-Rel, suggesting galectin-16-activated signal transduction pathways via the c-Rel hub in B or T cells at the maternal-fetal interface.

      Uniprot ID

      #A8MUM7

    • Sequence Note

      Ser2-Arg142

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant human Galectin-16.

    SDS-PAGE analysis of recombinant human Galectin-16.

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  • Datasheet & Documents
    MSDS
    Manual
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