Human TNFR2, His Tag, CHO

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Catalog Number

LDG113PHM

Datasheet

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• Specifications

  • Species of Origin

    Human

    Expression System

    CHO

  • Affinity Tag

    His Tag (C-term)

    Storage Buffer

    Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

  • Purity

    >90% as determined by SDS-PAGE analysis.

    Molecular weight

    The protein has a calculated 25.96 MW of kDa.
    The protein migrates as 35-45 kDa under reducing condition (SDS-PAGE analysis).

  • Activity

    Measured by its ability to inhibit TNF-alpha mediated cytotoxicity in L-929 cells in the presence of actinomycin D and 0.25 ng/mL recombinant mouse TNF-alpha, with the ED50 being < 0.1 µg/mL.

    Endotoxin Level

    <0.1 EU per 1 μg of the protein by the LAL method.

  • Mycoplasma

    Not detected

    Form

    Lyophilized

• Background

  • Background

    TNFR2 (Tumor Necrosis Factor Receptor 2) is involved in immune regulation and inflammation. It is expressed on immune cells and is studied in autoimmune diseases, cancer, and inflammation.

    Synonyms

    Tumor necrosis factor receptor superfamily member 1b, Tumor necrosis factor receptor 2, TNF-R2, Tumor necrosis factor receptor type II, TNF-RII, TNFR-II, p75, p80 TNF-alpha receptor, CD120b, Etanercept, membrane form, Tumor necrosis factor-binding protein 2, TBP-2, TBPII

  • Uniprot ID

    P20333

    Sequence Note

    Leu 23 - Asp 257

• Instruction

  • Reconstitution

    It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

    Shipping

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

  • Stability & Storage

    This product is stable after storage at:

    • -20°C for 12 months in lyophilized state from date of receipt.
    • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

    Avoid repeated freeze/thaw cycles.

• Image

  Human TNFR-2 Protein, His Tag, CHO (LDG113PHM) inhibits TNF-alpha mediated cytotoxicity in L-929 cells in the presence of actinomycin D and 0.25 ng/mL recombinant mouse TNF-alpha, with the ED50 being < 0.1 µg/mL.

  SDS-PAGE analysis of recombinant human TNFR2.

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• Datasheet & Documents

  Datasheet

  MSDS

  Manual

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Disclaimer：For Research Use or Further Manufacturing Only.