Mouse CD38, His Tag, CHO

Catalog Number

LDG018PMM

Datasheet

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• Specifications

  • Species of Origin

    Mouse

    Expression System

    CHO

  • Affinity Tag

    His Tag (C-term)

    Storage Buffer

    Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

  • Purity

    >95% as determined by SDS-PAGE analysis.

    Molecular weight

    The protein has a calculated MW of 30.61 kDa.
    The protein migrates as 36-42 kDa under reducing condition (SDS-PAGE analysis).

  • Endotoxin Level

    <0.1 EU per 1 μg of the protein by the LAL method.

    Form

    Lyophilized

• Background

  • Background

    CD38, a transmembrane glycoprotein, is widely expressed on immune cells such as B cells, T cells, and natural killer cells, as well as non-immune cells like endothelial cells. It functions as a multifunctional enzyme with ADP-ribosyl cyclase activity, catalyzing the conversion of NAD+ to cyclic ADP-ribose and nicotinic acid adenine dinucleotide phosphate. CD38 regulates calcium signaling, cell adhesion, and differentiation, playing essential roles in immune responses and inflammation. Moreover, CD38 is also a therapeutic target in multiple myeloma, where its expression correlates with disease progression. Understanding CD38's diverse functions is crucial for developing targeted therapies in immunology and oncology.

    Synonyms

    2'-phospho-ADP-ribosyl cyclase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-cyclic-ADP-ribose transferase, ADP-ribosyl cyclase 1 (ADPRC 1), Cyclic ADP-ribose hydrolase 1 (cADPR hydrolase 1), I-19, NIM-R5 antigen

  • Uniprot ID

    P56528

    Sequence Note

    Leu45-Thr304

• Instruction

  • Reconstitution

    It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 0.2 mg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

    Shipping

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

  • Stability & Storage

    This product is stable after storage at:

    • -20°C for 12 months in lyophilized state from date of receipt.
    • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

    Avoid repeated freeze/thaw cycles.

• Image

  SDS-PAGE analysis of recombinant mouse CD38.

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• Datasheet & Documents

  Datasheet

  MSDS

  Manual

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Disclaimer：For Research Use or Further Manufacturing Only.