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Leadgene Leadgene
Mouse CD4, His Tag, CHO
Catalog Number

LDG008PMM

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  • Specifications
    • Species of Origin

      Mouse

      Expression System

      CHO

    • Affinity Tag

      His Tag (C-term)

      Storage Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4

    • Purity

      >90% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 42.06 kDa.
      The protein migrates as 50-60 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin Level

      <0.1 EU per 1 μg of the protein by the LAL method.

      Form

      Lyophilized

  • Background
    • Background

      CD4 protein, primarily expressed on the surface of helper T cells, is a crucial component of the immune system. It plays a pivotal role in orchestrating the adaptive immune response by interacting with major histocompatibility complex class II molecules on antigen-presenting cells. This interaction facilitates T cell activation, leading to the production of cytokines and coordination of immune responses against pathogens. CD4 also serves as the primary receptor for human immunodeficiency virus (HIV), enabling viral entry into host cells. Understanding CD4's functions is essential for elucidating immune system regulation and developing therapies for immune-related disorders.

      Synonyms

      T-cell differentiation antigen L3T4, T-cell surface antigen T4/Leu-3

    • Uniprot ID

      NP_038516.1

      Sequence Note

      Met1-Thr394

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 0.2 mg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant mouse CD4.

    SDS-PAGE analysis of recombinant mouse CD4.

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  • Datasheet & Documents
    MSDS
    Manual
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