Mouse EpCAM, His Tag, CHO

Catalog Number

LDG020PMM

Datasheet

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• Specifications

  • Species of Origin

    Mouse

    Expression System

    CHO

  • Affinity Tag

    His Tag (C-term)

    Storage Buffer

    Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

  • Purity

    >95% as determined by SDS-PAGE analysis.

    Molecular weight

    The protein has a calculated MW of 28.46 kDa.
    The protein migrates as 30-35 kDa under reducing condition (SDS-PAGE analysis).

  • Endotoxin Level

    <0.1 EU per 1 μg of the protein by the LAL method.

    Form

    Lyophilized

• Background

  • Background

    EpCAM (Epithelial Cell Adhesion Molecule), a transmembrane glycoprotein, is expressed in epithelial tissues and various carcinomas. It mediates cell-cell adhesion and signaling, influencing cell proliferation, migration, and differentiation. EpCAM is involved in maintaining epithelial integrity and regulating epithelial-mesenchymal transition (EMT) during development and tissue repair. Additionally, it serves as a diagnostic and prognostic marker in cancer, where its overexpression correlates with tumor aggressiveness and poor clinical outcomes. EpCAM-targeted therapies, including monoclonal antibodies and immunotherapies, hold promise in cancer treatment. Understanding EpCAM's roles in physiology and pathology is crucial for developing effective therapeutic strategies.

    Synonyms

    Epithelial cell adhesion molecule, Epithelial glycoprotein 314 (EGP314; mEGP314), Protein 289A, Tumor-associated calcium signal transducer 1, CD326

  • Uniprot ID

    AAH05618.1

    Sequence Note

    Met1-Thr266

• Instruction

  • Reconstitution

    It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 0.2 mg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

    Shipping

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

  • Stability & Storage

    This product is stable after storage at:

    • -20°C for 12 months in lyophilized state from date of receipt.
    • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

    Avoid repeated freeze/thaw cycles.

• Image

  SDS-PAGE analysis of recombinant mouse EpCAM.

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• Datasheet & Documents

  Datasheet

  MSDS

  Manual

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Disclaimer：For Research Use or Further Manufacturing Only.