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Species of Origin
Mouse
Expression System
Escherichia coli
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Affinity Tag
His Tag (C-term)
Storage Buffer
Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
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Purity
>95% as determined by SDS-PAGE analysis.
Molecular weight
The protein has a calculated MW of 16.56 kDa.
The protein migrates about 17 kDa under reducing condition (SDS-PAGE analysis). -
Endotoxin Level
<0.1 EU per 1 μg of the protein by the LAL method.
Form
Lyophilized
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Specifications
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Background
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Background
Interleukin 31 (IL-31) is a 15.65 kDa cytokine with 141 amino acid residues. IL-31 is mainly secreted from Th2 cells and binds to a receptor called IL-31RA. Upon binding to IL-31RA, IL-31 activates several signal pathways like MAPK, PI3K/AKT, and Jak/STAT pathways. It is critical in regulating many biological functions, such as cell proliferation, hematopoiesis, induction of cytokines, inflammation, and immune response. It also responds to an antigen by facilitating cell-mediated immunity.
Synonyms
Interleukin-31, IL-31
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Uniprot ID
#Q6EAL8
Sequence Note
Thr24-Cys163
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Instruction
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Reconstitution
It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.
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Stability & Storage
This product is stable after storage at:
- -20°C for 12 months in lyophilized state from date of receipt.
- -20°C or -80°C for 1 month under sterile conditions after reconstitution.
Avoid repeated freeze/thaw cycles.
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Image
![SDS-PAGE analysis of recombinant mouse IL-31.]()
SDS-PAGE analysis of recombinant mouse IL-31.
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Publication
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Datasheet & Documents
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Disclaimer：For Research Use or Further Manufacturing Only.
