Mouse PSCA, His Tag, E. coli

Catalog Number

LDG096PME

Datasheet

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• Specifications

  • Species of Origin

    Mouse

    Expression System

    Escherichia coli

  • Affinity Tag

    His Tag (C-term)

    Storage Buffer

    Lyophilized from a 0.2 µm filtered solution of 50 mM Tris, 150 mM NaCl, 0.01% sarkosyl, pH 8.0

  • Purity

    >95% as determined by SDS-PAGE analysis.

    Molecular weight

    The protein has a calculated MW of 9.3 kDa.

  • Endotoxin Level

    <0.1 EU per 1 μg of the protein by the LAL method.

    Form

    Lyophilized

• Background

  • Background

    Prostate Stem Cell Antigen (PSCA) is a cell surface glycoprotein that is overexpressed in prostate cancer cells. PSCA plays a significant role in prostate cancer progression and metastasis by promoting tumor cell proliferation, invasion, and survival. It is also implicated in the modulation of signaling pathways involved in cell growth and apoptosis. Due to its specific expression in prostate cancer cells and its potential as a therapeutic target, PSCA has gained attention as a biomarker for prostate cancer diagnosis and prognosis. Moreover, PSCA-targeted therapies, such as monoclonal antibodies and antibody-drug conjugates, are being investigated for their efficacy in treating prostate cancer. Understanding the role of PSCA in prostate cancer biology is crucial for the development of novel diagnostic tools and therapeutic strategies for this prevalent malignancy.

    Synonyms

    Prostate stem cell antigen

  • Uniprot ID

    P57096

    Sequence Note

    Met1-Asn95

• Instruction

  • Reconstitution

    It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

    Shipping

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage

  • Stability & Storage

    This product is stable after storage at:

    • -20°C for 12 months in lyophilized state from date of receipt.
    • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

    Avoid repeated freeze/thaw cycles.

• Image

  SDS-PAGE analysis of recombinant mouse PSCA protein.

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• Datasheet & Documents

  Datasheet

  MSDS

  Manual

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Disclaimer：For Research Use or Further Manufacturing Only.