Swine IL-17A, His Tag, E. coli

Catalog Number

LDG016PSE

Datasheet

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• Specifications

  • Species of Origin

    Swine

    Expression System

    Escherichia coli

  • Affinity Tag

    His Tag (C-term)

    Storage Buffer

    Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

  • Purity

    >98% as determined by SDS-PAGE analysis.

    Molecular weight

    The protein has a calculated MW of 15.81 kDa.
    The protein migrates as 17-25 kDa under reducing condition (SDS-PAGE analysis).

  • Endotoxin Level

    <0.01 EU per 1 µg of the protein by the LAL method.

    Form

    Lyophilized

• Background

  • Background

    Interleukin 17-alpha (IL-17A) is a 14.54 kDa cytokine with 131 amino acid residues and is also referred to as CTLA-8. IL-17A is a proinflammatory cytokine mainly expressed in Th 17 cells, NK cells, and innate lymphoid cells (ILCs). After binding to the IL-17 receptor, IL-17A stimulates the production of IL-6, cyclooxygenase-2 (COX-2), and nitric oxide (NO) by activating NF-κB and MAPK signaling pathways. In addition, it also plays an essential role in against infection of extracellular bacteria and fungi by inducing epithelial cells to produce antimicrobial peptides.

    Synonyms

    Interleukin-17A, IL-17, IL-17A

  • Uniprot ID

    # XP_047652691 1

    Sequence Note

    Gly26-Ser155

• Instruction

  • Reconstitution

    It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

    Shipping

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

  • Stability & Storage

    This product is stable after storage at:

    • -20°C for 12 months in lyophilized state from date of receipt.
    • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

    Avoid repeated freeze/thaw cycles.

• Image

  SDS-PAGE analysis of recombinant swine IL-17A.

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• Datasheet & Documents

  Datasheet

  MSDS

  Manual

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Disclaimer：For Research Use or Further Manufacturing Only.