Anti-β-amyloid Antibody [Clone 85-1]

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Catalog Number

LDG0103YA

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• Overview

  Description

  Beta-amyloid (Aβ) is one of the intrinsically disordered proteins (IDPs) involved in Alzheimer's disease (AD) pathogenesis. This peptide derives from the sequential cleavage of a transmembrane glycoprotein, amyloid precursor protein (APP), by beta secretase and gamma secretase. The abnormal metabolism of APP result in excessive accumulation of Aβ, and triggers neurofibrillary tangles, oxidative stress, microglial activation, synaptic dysfunction, synaptic loss and the inflammatory response.

  Product Note

  Recommended dilution factor:
  ELISA: 1:5000-20000
  WB:1: 1000-5000
  
  
  
  Note: Working dilution for specific application should be determined by the investigator to obtain the best conditions.

• Specifications

  • Host

    Mouse

    Clonality

    Monoclonal

  • Isotype

    IgG2a

    Clone Name

    clone 85-1

  • Immunogen

    Human beta-amyloid 1-42

    Reactivity

    Human

  • Application

    ELISA, WB

    Conjugation

    Unconjugated

  • Concentration

    1 mg/mL

    Buffer

    Phosphate Buffered Saline containing 0.01% thimerosal, pH 7.4.

  • Specificity

    Beta Amyloid (1-42)

    Form

    Liquid

• Instruction

  • Shipping

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    Stability & Storage

    This product is stable after storage at:

    • 2-8°C for 2 weeks under sterile conditions from date of receipt.
    • -20°C or -80°C for 12 months under sterile conditions from date of receipt.

    Avoid repeated freeze/thaw cycles.
    Suggestion: Divide antibody into several vials. Keep only vials for usage at 2-8°C.

• Image

  ELISA titration of Anti-β-amyloid (1-42) Antibody [clone 85-1]

  Dot blot analysis of Anti-β-amyloid (1-42) Antibody [clone 85-1].

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• Datasheet & Documents

  Datasheet

  MSDS

  Manual

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Disclaimer：For Research Use or Further Manufacturing Only.