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Leadgene Leadgene
Anti-CD28 Antibody [Clone 0AA01]
Catalog Number

LDG0178YA

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  • Overview

    Description

    CD28, a well-known costimulatory receptor expressed on T cells, is a type I transmembrane glycoprotein of the Ig superfamily. When the T cells receive the first signal delivered by APCs (antigen-presenting cells), it initiates signaling cascades, which favor T cell survival and proliferation. It has been demonstrated that patients with lung cancer who responded to PD-1 therapy had more CD28+ T cells, suggesting that CD28 may predict treatment response.

    Product Note

    Recommended dilution factor:
    ELISA: 1:5000-20000

    Note: Working dilution for specific application should be determined by the investigator to obtain the best conditions.

  • Specifications
    • Clonality

      Humanized IgG

      Isotype

      IgG1

    • Clone Name

      clone 0AA01

      Reactivity

      Human

    • Application

      ELISA

      Conjugation

      Unconjugated

    • Concentration

      0.5 mg/mL

      Buffer

      Phosphate Buffered Saline containing 0.03% ProClin 300, pH 7.4.

    • Specificity

      CD28

      Form

      Liquid

  • Instruction
    • Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

      Stability & Storage

      This product is stable after storage at:

      • 2-8°C for 2 weeks under sterile conditions from date of receipt.
      • -20°C or -80°C for 12 months under sterile conditions from date of receipt.

      Avoid repeated freeze/thaw cycles.
      Suggestion: Divide antibody into several vials. Keep only vials for usage at 2-8°C.

  • Image
    ELISA titration of Anti-CD28 Chimeric IgG Antibody [Clone 0AA01] Titration curve of anti-CD28 antibody in ELISA.

    ELISA titration of Anti-CD28 Chimeric IgG Antibody [Clone 0AA01]
    Titration curve of anti-CD28 antibody in ELISA.

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  • Datasheet & Documents
    MSDS
    Manual
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