Description
D-3-Hydroxybutyrate dehydrogenase (3-HBDH) is an enzyme crucial in the metabolism of ketone bodies, specifically involved in the conversion of D-3-hydroxybutyrate to acetoacetate during ketogenesis. 3-HBDH plays a vital role in energy production, particularly under conditions such as fasting or prolonged exercise when ketone bodies serve as alternative energy sources. This enzyme is essential for maintaining metabolic balance and is found in various tissues, including the liver and kidneys. Understanding 3-HBDH's function is significant for insights into metabolic disorders and energy metabolism regulation.