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Species of Origin
Human
Expression system
CHO
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Affinity Tag
Tag Free
Buffer
Lyophilized from a 0.2 μm-filtered solution containing 100 mM Glycine, 150 mM NaCl, and 0.01% Tween 80, pH 4.0
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Purity
>95% as determined by SDS-PAGE analysis.
Molecular weight
The protein has a calculated MW of 12.9 kDa.
The protein migrates as 13 kDa under reducing condition (SDS-PAGE analysis). -
Activity
Measure by its ability to inhibit the proliferation of mouse MPC-11 cells. The ED₅₀ for this effect is <10 ng/mL.
Endotoxin level
<0.1 EU per 1 μg of the protein by the LAL method.
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Form
Lyophilized
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Specifications
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Background
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Background
Activin is the member of the TGF beta superfamily of cytokines. The current understanding of Activin A is classified as a hormone, a Growth Factors, and a cytokine. Depending on the different cell type, that overexpression of Activin A can either inhibit or promote cells division. There are important implications for tumor biology. Activin A also increase joint inflammation in rheumatoid arthritis (RA) and induces pathogenic mechanisms in the respiratory system.
Synonyms
INHBA, Inhibin beta A, FSH releasing protein.
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Uniprot ID
P08476
Sequence Note
Gly311-Ser426
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Instruction
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Reconstitution
It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.
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Stability & Storage
This product is stable after storage at:
● -20°C for 12 months in lyophilized state from date of receipt.
● -20°C or -80°C for 1 month under sterile conditions after reconstitution.
Avoid repeated freeze/thaw cycles.
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Image
![Measure by its ability to inhibit the proliferation of mouse MPC-11 cells. The ED₅₀ for this effect is <10 ng/mL.]()
Measure by its ability to inhibit the proliferation of mouse MPC-11 cells. The ED₅₀ for this effect is <10 ng/mL.
![SDS-PAGE analysis of recombinant Human Activin A.]()
SDS-PAGE analysis of recombinant Human Activin A.
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Publication
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Datasheet & Documents
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Disclaimer：For Research Use or Further Manufacturing Only.
