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Leadgene Leadgene
Human Lipoprotein a, (Lp(a)), Tag free
Catalog Number

LDG0001NH

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  • Overview

    Product Note

    Human Lipoprotein is a native protein isolated from human serum

  • Specifications
    • Species of Origin

      Human

      Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4., with 0.01% HSA

    • Purity

      >80% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 39 kDa. The protein migrates as 48 kDa under reducing condition (SDS-PAGE analysis).

    • Mycoplasma

      Not detected

      Form

      Lyophilized

  • Background
    • Background

      Lipoprotein(a), or Lp(a), is a lipoprotein composed of LDL and apolipoprotein(a), which is covalently attached to apolipoprotein B-100. Its plasma levels are primarily determined by genetics and vary widely among individuals. Elevated Lp(a) is an independent risk factor for cardiovascular diseases, including coronary artery disease, stroke, and aortic stenosis. Its structural similarity to plasminogen may impair fibrinolysis, contributing to its proatherogenic and prothrombotic effects. Despite its clinical importance, effective treatments to lower Lp(a) are limited. Measuring Lp(a) is increasingly used to identify individuals with elevated cardiovascular risk.

      Synonyms

      Apolipoprotein(a), Apo(a), Lp(a), LPA

    • Uniprot ID

      P08519

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:
      ● -20°C for 12 months in lyophilized state from date of receipt.
      ● -20°C or -80°C for 1 month under sterile conditions after reconstitution.
      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of Human Lipoprotein a.

    SDS-PAGE analysis of Human Lipoprotein a.

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  • Datasheet & Documents
    MSDS
    Manual
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