-
Species of Origin
Human
Expression system
HEK293
-
Affinity Tag
His Tag (C-term)
Buffer
Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
-
Purity
>95% as determined by SDS-PAGE analysis.
Molecular weight
The protein has a calculated MW of 19.21 kDa.
The protein migrates as 20 kDa under reducing condition (SDS-PAGE analysis). -
Endotoxin level
<0.1 EU per 1 μg of the protein by the LAL method.
Form
Lyophilized
-
Specifications
-
Background
-
Background
M-CSF, or Macrophage Colony-Stimulating Factor, is a crucial growth factor that drives the production and development of macrophages, essential cells in the immune system. It stimulates the differentiation of stem cells into macrophages and promotes their survival and activity. M-CSF plays a vital role in various immune responses, including fighting infections, wound healing, and tissue repair. It also contributes to bone metabolism and lipoprotein clearance. Dysregulation of M-CSF signaling can contribute to inflammatory diseases and certain cancers. Therefore, M-CSF is an important therapeutic target for various conditions, and its levels can be used as a biomarker for disease progression.
Synonyms
CSF-1, Lanimostim, Proteoglycan macrophage colony-stimulating factor (PG-M-CSF)
-
Uniprot ID
P09603
Sequence Note
Glu33-Gln181
-
-
Instruction
-
Reconstitution
It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 0.2 mg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.
-
Stability & Storage
This product is stable after storage at:
- -20°C for 12 months in lyophilized state from date of receipt.
- -20°C or -80°C for 1 month under sterile conditions after reconstitution.
Avoid repeated freeze/thaw cycles.
-
-
Image
1/1 -
Review
Help others learn more about this product. Use the link below to share your experience.
-
Publication
There are currently no publications. Use the link below to let us know.
-
Datasheet & Documents
1/1
Disclaimer:For Research Use or Further Manufacturing Only.