Human Trop-2, His Tag, CHO

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Catalog Number

LDG108PHM

Datasheet

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• Specifications

  • Species of Origin

    Human

    Expression system

    CHO

  • Affinity Tag

    His Tag (C-term)

    Buffer

    Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

  • Purity

    >90% as determined by SDS-PAGE analysis.

    Molecular weight

    The protein has a calculated 28.71 MW of kDa.
    The protein migrates as 25-45 kDa under reducing condition (SDS-PAGE analysis).

  • Activity

    Measured by the ability of the immobilized protein to support the adhesion of U937 human histiocytic lymphoma cells. The ED50 for this effect is <10 μg/mL.

    Endotoxin level

    <0.1 EU per 1 μg of the protein by the LAL method.

  • Mycoplasma

    Not detected

    Form

    Lyophilized

• Background

  • Background

    Trop-2 is a transmembrane glycoprotein overexpressed in many cancers, associated with tumor growth and metastasis. It is a target for antibody-drug conjugates in cancer therapy.

    Synonyms

    Tumor-associated calcium signal transducer 2, Cell surface glycoprotein Trop-2, Membrane component chromosome 1 surface marker 1, Pancreatic carcinoma marker protein GA733-1

  • Uniprot ID

    P09758

    Sequence Note

    His27-Thr274

• Instruction

  • Reconstitution

    It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

    Shipping

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

  • Stability & Storage

    This product is stable after storage at:

    • -20°C for 12 months in lyophilized state from date of receipt.
    • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

    Avoid repeated freeze/thaw cycles.

• Image

  Measured by the ability of the immobilized protein to support the adhesion of U937 human histiocytic lymphoma cells. The ED50 for this effect is <10 μg/mL.
  Activity analysis of recombinant Human Trop-2, His Tag, CHO.

  SDS-PAGE analysis of recombinant human Trop-2.

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• Datasheet & Documents

  Datasheet

  MSDS

  Manual

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Disclaimer：For Research Use or Further Manufacturing Only.