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Species of Origin
Mouse
Expression system
CHO
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Affinity Tag
His Tag (C-term)
Buffer
Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4
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Purity
>95% as determined by SDS-PAGE analysis.
Molecular weight
The protein has a calculated MW of 30.38 kDa.
The protein migrates as 30-42 kDa under reducing condition (SDS-PAGE analysis). -
Endotoxin level
<0.1 EU per 1 μg of the protein by the LAL method.
Form
Lyophilized
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Specifications
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Background
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Background
CD19 protein, present on the surface of B cells, acts as a key regulator of B cell development and function. It plays a crucial role in B cell receptor (BCR) signaling, promoting B cell activation, proliferation, and differentiation upon antigen recognition. CD19 also enhances B cell responsiveness to co-stimulatory signals from T cells. Due to its selective expression on B cells and absence on other immune cells, CD19 serves as a valuable target for immunotherapy in B cell malignancies such as B cell lymphomas and leukemias. Understanding CD19 biology is essential for developing targeted therapies for B cell-associated disorders.
Synonyms
Differentiation antigen CD19, B-lymphocyte antigen CD19
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Uniprot ID
P25918
Sequence Note
Met1-Gly287
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Instruction
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Reconstitution
It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 0.2 mg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.
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Stability & Storage
This product is stable after storage at:
- -20°C for 12 months in lyophilized state from date of receipt.
- -20°C or -80°C for 1 month under sterile conditions after reconstitution.
Avoid repeated freeze/thaw cycles.
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Publication
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Datasheet & Documents
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Disclaimer:For Research Use or Further Manufacturing Only.