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Species of Origin
Mouse
Expression system
CHO
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Affinity Tag
His Tag (C-term)
Buffer
Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4
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Purity
>95% as determined by SDS-PAGE analysis.
Molecular weight
The protein has a calculated MW of 47.2 kDa.
The protein migrates as 60-75 kDa under reducing condition (SDS-PAGE analysis). -
Endotoxin level
<0.1 EU per 1 μg of the protein by the LAL method.
Form
Lyophilized
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Specifications
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Background
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Background
CD36, a transmembrane glycoprotein, is widely expressed on various cell types including macrophages, adipocytes, and endothelial cells. It serves as a multifunctional receptor involved in lipid metabolism, inflammation, and immune responses. CD36 facilitates the uptake of fatty acids, oxidized low-density lipoproteins (LDL), and other lipid molecules, contributing to cellular lipid homeostasis and foam cell formation in atherosclerosis. Additionally, CD36 recognizes and binds to a diverse range of ligands including microbial pathogens, apoptotic cells, and thrombospondin-1, mediating phagocytosis, innate immune responses, and tissue remodeling. Understanding CD36's diverse functions is crucial for elucidating its roles in health and disease.
Synonyms
Glycoprotein IIIb (GPIIIB), PAS IV, PAS-4, Platelet glycoprotein IV (GPIV)
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Uniprot ID
Q08857
Sequence Note
Gly30-Lys439
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Instruction
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Reconstitution
It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 0.2 mg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.
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Stability & Storage
This product is stable after storage at:
- -20°C for 12 months in lyophilized state from date of receipt.
- -20°C or -80°C for 1 month under sterile conditions after reconstitution.
Avoid repeated freeze/thaw cycles.
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Review
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Publication
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Datasheet & Documents
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Disclaimer:For Research Use or Further Manufacturing Only.