Language
EN
Leadgene Leadgene
Mouse CD36, His Tag, CHO
Catalog Number

LDG011PMM

More Documents
Loading package & price...
  • Specifications
    • Species of Origin

      Mouse

      Expression system

      CHO

    • Affinity Tag

      His Tag (C-term)

      Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 47.2 kDa.
      The protein migrates as 60-75 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin level

      <0.1 EU per 1 μg of the protein by the LAL method.

      Form

      Lyophilized

  • Background
    • Background

      CD36, a transmembrane glycoprotein, is widely expressed on various cell types including macrophages, adipocytes, and endothelial cells. It serves as a multifunctional receptor involved in lipid metabolism, inflammation, and immune responses. CD36 facilitates the uptake of fatty acids, oxidized low-density lipoproteins (LDL), and other lipid molecules, contributing to cellular lipid homeostasis and foam cell formation in atherosclerosis. Additionally, CD36 recognizes and binds to a diverse range of ligands including microbial pathogens, apoptotic cells, and thrombospondin-1, mediating phagocytosis, innate immune responses, and tissue remodeling. Understanding CD36's diverse functions is crucial for elucidating its roles in health and disease.

      Synonyms

      Glycoprotein IIIb (GPIIIB), PAS IV, PAS-4, Platelet glycoprotein IV (GPIV)

    • Uniprot ID

      Q08857

      Sequence Note

      Gly30-Lys439

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 0.2 mg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant mouse CD36.

    SDS-PAGE analysis of recombinant mouse CD36.

    1
    /
    1
    Total   (1)
  • Review

    Help others learn more about this product. Use the link below to share your experience.

  • Publication

    There are currently no publications. Use the link below to let us know.

  • Datasheet & Documents
    MSDS
    Manual
    1
    /
    1

Disclaimer:For Research Use or Further Manufacturing Only.

This site uses cookies as described in our Privacy Policy in order to improve your user experience and deliver customized advertising to you. Click “I Agree” to consent and continue.