Mouse CD4, His Tag, CHO

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Catalog Number

LDG008PMM

Datasheet

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• Specifications

  • Species of Origin

    Mouse

    Expression system

    CHO

  • Affinity Tag

    His Tag (C-term)

    Buffer

    Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4

  • Purity

    >90% as determined by SDS-PAGE analysis.

    Molecular weight

    The protein has a calculated MW of 42.06 kDa.
    The protein migrates as 50-60 kDa under reducing condition (SDS-PAGE analysis).

  • Endotoxin level

    <0.1 EU per 1 μg of the protein by the LAL method.

    Form

    Lyophilized

• Background

  • Background

    CD4 protein, primarily expressed on the surface of helper T cells, is a crucial component of the immune system. It plays a pivotal role in orchestrating the adaptive immune response by interacting with major histocompatibility complex class II molecules on antigen-presenting cells. This interaction facilitates T cell activation, leading to the production of cytokines and coordination of immune responses against pathogens. CD4 also serves as the primary receptor for human immunodeficiency virus (HIV), enabling viral entry into host cells. Understanding CD4's functions is essential for elucidating immune system regulation and developing therapies for immune-related disorders.

    Synonyms

    T-cell differentiation antigen L3T4, T-cell surface antigen T4/Leu-3

  • Uniprot ID

    NP_038516.1

    Sequence Note

    Met1-Thr394

• Instruction

  • Reconstitution

    It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 0.2 mg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

    Shipping

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

  • Stability & Storage

    This product is stable after storage at:

    • -20°C for 12 months in lyophilized state from date of receipt.
    • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

    Avoid repeated freeze/thaw cycles.

• Image

  Mouse CD4 Protein, His Tag, CHO (LDG008PMM) supports the adhesion of NIH-3T3 mouse embryonic fibroblast cells, with the ED50 ranging from 1 to 10 μg/mL.

  SDS-PAGE analysis of recombinant mouse CD4.

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• Datasheet & Documents

  Datasheet

  MSDS

  Manual

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Disclaimer：For Research Use or Further Manufacturing Only.