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Leadgene Leadgene
Mouse CDX2, His Tag, CHO
Catalog Number

LDG025PMM

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  • Specifications
    • Species of Origin

      Mouse

      Expression system

      CHO

    • Affinity Tag

      His Tag (C-term)

      Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >95% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 24.3 kDa.
      The protein migrates as 35-50 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin level

      <0.1 EU per 1 μg of the protein by the LAL method.

      Form

      Lyophilized

  • Background
    • Background

      CDX2 (Caudal Type Homeobox 2) protein is a transcription factor crucial for intestinal development and homeostasis. It regulates the expression of genes involved in intestinal epithelial differentiation, cell proliferation, and barrier function. CDX2 is predominantly expressed in the intestinal epithelium, where it plays a key role in maintaining intestinal integrity and function. Dysregulation of CDX2 expression is associated with intestinal disorders, including inflammatory bowel disease and colorectal cancer. Understanding CDX2's functions in intestinal biology is essential for elucidating the molecular mechanisms underlying gastrointestinal diseases and developing targeted therapies for these conditions.

      Synonyms

      Homeobox protein CDX-2, Caudal-type homeobox protein 2

    • Uniprot ID

      P43241

      Sequence Note

      Met1-Gln311

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 0.2 mg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant mouse CDX2.

    SDS-PAGE analysis of recombinant mouse CDX2.

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  • Datasheet & Documents
    MSDS
    Manual
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