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Leadgene Leadgene
Mouse PCSK9, His Tag, CHO
Catalog Number

LDG084PMM

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  • Specifications
    • Species of Origin

      Mouse

      Expression system

      CHO

    • Affinity Tag

      His Tag (C-term)

      Buffer

      Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

    • Purity

      >80% as determined by SDS-PAGE analysis.

      Molecular weight

      The protein has a calculated MW of 75.64 kDa.
      The protein migrates as 10-60 kDa under reducing condition (SDS-PAGE analysis).

    • Endotoxin level

      <0.1 EU per 1 μg of the protein by the LAL method.

      Mycoplasma

      Not detected

    • Form

      Lyophilized

  • Background
    • Background

      PCSK9 is a protein that regulates cholesterol homeostasis by promoting the degradation of LDL receptors. It is a target for therapies aimed at lowering cholesterol levels in cardiovascular diseases.

      Synonyms

      Proprotein convertase subtilisin/kexin type 9, EC:3.4.21.-, Neural apoptosis-regulated convertase 1, NARC-1, Proprotein convertase 9, PC9, Subtilisin/kexin-like protease PC9

    • Uniprot ID

      Q80W65

      Sequence Note

      Gln35-Gln 694

  • Instruction
    • Reconstitution

      It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

      Shipping

      The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

    • Stability & Storage

      This product is stable after storage at:

      • -20°C for 12 months in lyophilized state from date of receipt.
      • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

      Avoid repeated freeze/thaw cycles.

  • Image
    SDS-PAGE analysis of recombinant mouse PCSK9.

    SDS-PAGE analysis of recombinant mouse PCSK9.

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  • Datasheet & Documents
    MSDS
    Manual
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