Mouse TNFR-2, His Tag, CHO

Catalog Number

LDG016PMM

Datasheet

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• Specifications

  • Species of Origin

    Mouse

    Expression system

    CHO

  • Affinity Tag

    His Tag (C-term)

    Buffer

    Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

  • Purity

    >95% as determined by SDS-PAGE analysis.

    Molecular weight

    The protein has a calculated MW of 26.14 kDa.
    The protein migrates as 35-50 kDa under reducing condition (SDS-PAGE analysis).

  • Endotoxin level

    <0.1 EU per 1 μg of the protein by the LAL method.

    Form

    Lyophilized

• Background

  • Background

    TNFR-2, or Tumor Necrosis Factor Receptor 2, is a transmembrane protein found on the surface of various cell types, including immune cells and endothelial cells. It serves as a receptor for Tumor Necrosis Factor-alpha (TNF-alpha), a cytokine involved in inflammation and immune regulation. TNFR-2 signaling modulates cell survival, proliferation, and immune responses, playing a critical role in tissue homeostasis and host defense. Dysregulation of TNFR-2 has been implicated in autoimmune diseases, inflammatory disorders, and cancer. Understanding the molecular mechanisms underlying TNFR-2 signaling is essential for developing targeted therapies to modulate immune responses and treat associated diseases.

    Synonyms

    Tumor necrosis factor receptor 2 (TNF-R2), Tumor necrosis factor receptor type II (TNF-RII; TNFR-II), p75, p80 TNF-alpha receptor, CD120b

  • Uniprot ID

    P25119

    Sequence Note

    Met1-Gly258

• Instruction

  • Reconstitution

    It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 0.2 mg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

    Shipping

    The product is shipped with polar packs. Upon receipt, store it immediately at -20°C or lower for long term storage.

  • Stability & Storage

    This product is stable after storage at:

    • -20°C for 12 months in lyophilized state from date of receipt.
    • -20°C or -80°C for 1 month under sterile conditions after reconstitution.

    Avoid repeated freeze/thaw cycles.

• Image

  SDS-PAGE analysis of recombinant mouse TNFR-2.

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• Datasheet & Documents

  Datasheet

  MSDS

  Manual

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Disclaimer：For Research Use or Further Manufacturing Only.