FOPPR™ Epitope Binning Service

FOPPR

Leadgene offers you a new platform, FOPPR™ INB-D200, for epitope binning service.

It can quickly identify whether antibody clones occupy the same or different epitopes.

The possibility of antibody pairing or co-treatment can also be evaluated by this service.

FOPPR™ Technology

The unique & patented FOPPR™ Technology is combining optical waveguides with noble metal nanoparticles for the sensitive and reliable detection of molecules. In FOPPR™, gold nanoparticles (AuNPs) are in close proximity to an unclad optical fiber. As light propagates within the optical fiber, total internal reflection (TIR) results in an evanescent field that induces the AuNPs to undergo particle plasmon resonance (PPR). When target-analytes interact to AuNPs - conjugated ligands, it will lead to a change of refractive index near the sensing surface.

The extreme sensitivity of this optical property to changes in the surrounding environment makes FOPPR™ an ideal technology for monitoring real-time interactions between a wide range of molecular species, including but not limited to organic drugs, oligonucleotides, proteins, and viruses.

What we can do

The new platform - FOPPR™ INB-D200
Execute 2 to 4 antibody clones epitope binning with a short of analysis time
Time and cost-saving compared to the traditional antibody-paring method
Full and detail discussion

FOPPR

Service workflow:

Pre-discussion and quotation
Case confirmation
Case opening
Sample providing
Affinity analysis
Final report delivery
Result discussion
Case completion

For detailed sample requirements, please contact us directly.
• Purity ≥ 80%
• Concentration ≥ 0.64 mg/mL
• Volume ≥ 100 µL
Deliverables:
• A final report (with sample information, affinity results of each pair of samples, including ka, kd and KD, and a epitope binning result of one injection order of antibodies).

Related Services:

Biacore™ kinetic measurement service

Antibody pairing service

FOPPR™ affinity analysis service

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