Recombinant Antibody Production

Recombinant antibody production technology is an indispensable process for antibody humanization during therapeutic antibody development.

Leadgene has a well-established technology and experience in producing high quality antibodies.

We provide a dedicated team to help you produce recombinant antibody for your research requirements.

• Key service features:
  • Professional antibody sequence evaluation and optimization.
  • Various constant region backbone choices.
     Human: IgG1 or IgG4 S108P
     Mouse: IgG1, IgG2a or IgG2b
     Rabbit: IgG
  • Small scale expression test depends on your requirements.
  • Flexible choice of antibody expression level of cell culture volume.
• Service workflow:
  • Antibody sequence evaluation
  • Choose the constant region backbone
  • Gene synthesis and plasmid construction (VH-CH/VL-CL)
  • Antibody expression and purification
• Sample requirements:
  • Provide the sequence of antibody variable region
• Deliverables:
  • Final report antibodies validation by SDS-PAGE)
  • Expression plasmid (Heavy chain and Light chain)
  • Purified antibodies